10 things you need to know before starting a PhD degree

I have recently graduated from the University of Manchester with a PhD in Plant Sciences after four difficult, but enjoyable, years. During those four years, I often felt slightly lost – and there was more than one occasion on which I didn’t even want to imagine writing up my thesis in fear of delving into fits of panic.

On reflection, I realise that – to quote a colleague – commencing my PhD was like “jumping in the deep end with your eyes closed.” If only I’d known to take a deep breath.

Let’s be under no false impressions, completing a PhD isn’t easy. There will be times when you feel like Wile E Coyote chasing after the Roadrunner – a little bit out of your depth a lot of the time. It’s four years of your life, so make sure it is what you really want to do.

If you want to pursue a career in science, a PhD isn’t always necessary.

It is possible to make great inroads into industry without a doctoral degree. That said, a PhD can also be a very useful qualification with many transferable skills to add to your CV.

By the time you’ll have finished, you can include essentials such as time management, organisational skills, prioritising workloads, attention to detail, writing skills, presenting to an audience – and most importantly – resilience, to name but a few.

This is very important.

Time after time, our experienced scientists at EI, including Erik Van-Den-Bergh (and I agree) say, “make sure you’re extremely passionate about exactly that subject.” When I saw the PhD opening that I eventually was offered, I remember being demonstrably ecstatic about the project before I’d even started it.

I was always interested in calcium signalling and organised a meeting with my potential supervisor immediately, which (to quote Billy Connolly) I leapt into in a mood of gay abandon.

Not only does this help you to keep engaged with your project even through the painstakingly slow times, it also greatly enhances your ability to sell yourself in an interview. If you can show passion and enthusiasm about the project and the science then you’ll be that one step ahead of other candidates – which is all the more important now that many studentships are competitive.

You have to be the best out of many, often exceptional candidates.

However, as important as it is to be passionate about your project, make sure that the person who will be supervising you is worthy.

Does your potential supervisor have a prolific track record of publishing work? What is the community of scientists like in the lab you may be working in? Are there experienced post-doctoral scientists working in the lab? Who will your advisor be? Is your supervisor an expert in the field you are interested in? Is the work you will be doing ground-breaking and novel, or is it quite niche?

There is nothing more frustrating – and I know many PhD degree students with this problem – than having a supervisor who is rarely there to talk to, shows little interest in your work, and cannot help when you are struggling in the third year of your project and some guidance would be much appreciated.

Personally, and I was very lucky to have this, I think it’s incredibly useful to have two supervisors. My PhD degree was split between the University of Manchester and the Marine Biological Association in Plymouth. Between my supervisors, I had two people with expertise in different fields, who could give me some fantastic advice from different perspectives. This also meant that I had two people to check through my thesis chapters and provide useful comments on my drafts.

Felix Shaw – one of our bioinformatics researchers at EI – put it best when he said, “it felt like I was running into brick walls all the way through [my PhD]… you’d run into a brick wall, surmount it, only to run straight into another.”

It’s true.

You’ll find that, often, experiments don’t work. What might seem like a great idea could turn out to be as bad as choosing to bat first on a fresh wicket on the first day of the third Ashes test at Edgbaston. (Yeah, we don't know what that means either - Ed).

Resilience is key while completing your PhD. Be open to change and embrace the chance to experiment in different ways. You might even end up with a thesis chapter including all of your failures, which at the very least is something interesting to discuss during your viva voce.

As a PhD student, you are a complete novice in the world of science and most things in the lab will be – if not new to you – not exquisitely familiar. This matters not, if you take advantage of the people around you.

Firstly, there are lab technicians and research assistants, who have probably been using the technique you are learning for years and years. They are incredibly experienced at a number of techniques and are often very happy to help show you how things are done.

There are postdocs and other PhD students, too. Not only can they help you with day-to-day experiments, they can offer a unique perspective on how something is done and will probably have a handy back-catalogue of fancy new techniques to try.

There are also a bunch of PIs, not limited to your own, who are great to talk to. These people run labs of their own, have different ideas, and might even give you a job once you’ve completed your PhD.

Don’t limit yourself to the labs directly around you, however. There are a massive number of science conferences going on all around the world. Some of them, such as the Society of Biology Conference, take place every year at a similar time in different locations, attracting many of the leaders in their respective fields.

If you are terrified by the prospect of speaking at a full-blown science conference and having your work questioned by genuine skeptics, there are also many student-led conferences which will help you dangle your fresh toes in the murky waters of presenting your work.

One such conference, the Second Student Bioinformatics Symposium, which took place at Earlham Institute in October 2016, was a great place for candidates to share their projects with peers, who are often much more friendly than veteran researchers with 30 year careers to their name when it comes to the questions at the end of your talk.

Another great reason to attend conferences, of course, is the social-side too – make the most of this. You never know who you might meet and connect with over a few drinks once the talks are over and the party commences.

You should be aware that for every 200 PhD students, only 7 will get a permanent academic post, so it’s incredibly unlikely that you’ll become a Professor – and even if you make PI, it probably won’t be until your mid-forties.

You may also, despite having commenced along the academic path, decide that actually, working in a lab environment isn’t for you. Most PhD graduates, eventually, will not pursue an academic career, but move on to a wide range of other vocations.

It might be that Science Communication is more up your street. This was certainly the case for me – and I made sure that I took part in as many public engagement events as possible while completing my PhD. Most Universities have an active public engagement profile, while organisations such as STEM can provide you with ample opportunities to interact with schools and the general public.

You might also consider entrepreneurship as a route away from academia, which might still allow you to use your expert scientific knowledge. There are a variety of competitions and workshops available to those with a business mind, a strong example being Biotechnology YES.

I, for example, took part in the Thought for Food Challenge, through which I have been able to attend events around the world and meet a vast array of like-minded individuals. Many of the participants from the challenge have gone on to set up successful businesses and have even found jobs as a result of the competition.

Remember that you still have a life outside of your PhD degree – and that this can be one of the greatest opportunities to make amazing friends from around the world.

A science institute is usually home to the brightest students from a variety of countries and can provide a chance to experience a delightful range of different people and cultures. Don’t just stick to the people in your lab, go to events for postgraduate students and meet people from all over campus.

There are usually academic happy hours happening on Fridays after work where you can buy cheap beer, or some lucky institutions even have their own bar. At Norwich Research Park, we not only have the Rec Centre, along with bar, swimming pool, calcetto, samba classes, archery, and a range of other activities, but there are also biweekly “Postdoc pub clubs” which are very fun to join on a Tuesday evening.

Maintain your hobbies and keep up with friends outside of your PhD and you’ll probably find it’s not that gruelling a process after all.

Plus, the people you meet and become friends with might be able to help you out – or at least be able to offer a sympathetic shoulder.

If, after reading all of this, you’re still going to march forth and claim your doctorhood, then this section should be rather useful.

Firstly, make sure your data is backed up. It’s amazing how many people don’t do this and you’d be bonkers not to. Keep your work saved on a shared drive, so that if your computer decides to spontaneously combust upon pressing the return key, you won’t have lost all of your precious work – or have to go through every one of your lab books and type it all up again.

Secondly, don’t leave your bag in the pub with your half-written thesis in it. I did this, the bag was fine, I was in a state of terror for at least half an hour before the kind person at Weatherspoons located said bag.

Thirdly, read. Read broadly, read anything and everything that’s closely related to your project – or completely unrelated. It’s sometimes amazing where you might find a stroke of inspiration, a new technique you hadn’t thought of … or even in idea of where you might like to go next.

Finally, ask questions – all of the time. No matter how stupid it might sound in your head, everyone’s probably been asked it before, and if you don’t ask, you don’t get.

You’ll probably look far less stupid if you just ask the person standing next to you how the gradient PCR function works on your thermal cycler rather than standing there randomly prodding buttons and looking flustered, anyway.