UK Conference of Bioinformatics and Computational Biology (UK-CBCB)
How to manage biological data and use computational methods to power life science research
How to manage biological data and use computational methods to power life science research
Modern life science research is increasingly reliant on data science, and a failure to keep pace with computational methods will leave UK life science research treading water.
In partnership with ELIXIR-UK, the UK-CBCB conference will cover the breadth of biological data management, analysis and sharing.
This three-day event will combine a keynote lecture with presentations of use cases from researchers working at the cutting edge, plus breakout discussion groups where participants can exchange expertise and challenges with one another, working to provide multidisciplinary solutions to complex problems together.
In order to maximise engagement across multiple disciplines in this online event, we have opted for a streamlined programme (no parallel sessions), short introductory talks and targeted breakout discussion groups to focus on particular challenges underpinned by a biological question. There will be numerous breakout discussions in each themed session, based upon the flash presentations from our research facilitators.
The confirmed themes for this event are:
Who is this event for?
UK-CBCB is designed to bring together researchers from a range of research backgrounds to explore and discuss challenges faced at the very cutting edge of research in these fields.
We want this year’s event to be as engaging and openly accessible as possible, so we expect the broad range of topics to be introduced for novices but with cutting edge case studies to attract even the most experienced researchers. Therefore we welcome all researchers across the spectrum of career points from postgraduate students to professors and those managing resources and infrastructures.
We particularly encourage early career researchers and PhD students to attend in order to gain exposure to the breadth of computational approaches in data-intensive bioscience with ample opportunity to hear from experts working at the cutting edge as well as those making tentative steps into the fields of discussion to learn of the challenges faced when entering the field.
Notice to event attendees – Payment Issues
We are aware of an issue affecting a small number of registrants paying for our events by card as a result of increased 3D secure protocols introduced by banks. Card transactions are handled by an external party and we are awaiting a resolution.
If you are experiencing issues with payment by card, please reach out to your bank in the first instance. If they are unable to assist you please email training@earlham.ac.uk with the name of the person trying to register, their email address and event name. We will be able to offer you an alternative payment method.
In partnership with ELIXIR-UK
Welcome to the 2022 UK-CBCB
Neil Hall, Director of the Earlham Institute and Joint Head of Node of Elixir-UK
Session 1: Metagenomics and Microbial Bioinformatics
Session Lead: Rob Finn, European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI)
Talk 1: Luiz Irber, Computational Biologist, 10x Genomics
Content-Based Petabase-Scale Search with Fractional Sketches
Talk 2: Robert Griffiths, Molecular Microbial Ecologist, UK Centre for Ecology and Hydrology
Genes across landscapes: ecological approaches toward synthesis of microbiome diversity & function
Talk 3: Lorna Richardson, Microbiome Resources Co-ordinator, European Bioinformatics Institute (EMBL-EBI)
MGnify data products for reference-based analysis and metagenomic mining
Break
Breakout Discussions: Metagenomics and Microbial Bioinformatics
Luiz Irber, Robert Griffiths and Lorna Richardson with Rob Finn
Summary of Metagenomics and Microbial Bioinformatics
Rob Finn
Lunch
Session 2: Bioimaging and Artificial Intelligence
Session Lead: Jean-Marie Burel, Senior Software Architect, University of Dundee
Talk 1: Yang Zhang, Project Scientist & Project Manager, Carnegie Mellon University (US
Nucleome Browser: An integrative and multimodal data navigation platform for 4D Nucleome
Talk 2: Matthew Hartley, BioImage Archive Team Leader, European Bioinformatics Institute (EMBL-EBI)
Open bioimaging data at scale: publication, analysis and reuse
Talk 3: Josh Moore, Senior Software Architect, University of Dundee
OME-NGFF (next-generation file format): Zarr as a cloud-native solution for FAIRer bioimaging data
Break
Breakout Discussions:
Josh Moore, Matthew Hartley and Jian Ma
Summary of Bioimaging and Artificial Intelligence
Jean-Marie Burel
Session 3: Sex and Gender Bias in Computational Disciplines
Session Lead: Franca Fraternali, Randall Centre for Cell and Molecular Biophysics
Talk 1: Alba Jené Sanz, Bioinformatics Unit Coordinator, Barcelona Supercomputing Centre
The Bioinfo4Women programme: promoting gender equity and diversity for science at the BSC
Talk 2: Elena Bernabeu, PostDoctoral Fellow, Institute of Genetics and Cancer, University of Edinburgh
Unravelling the effect of sex on human genetic architecture
Talk 3: Segun Fatumo, Associate Professor, MRC/UVRI Uganda and London School of Hygiene and Tropical Medicine
Ethnic bias in genomics studies
Breakout Discussions:
Alba Jené Sanz, Elena Bernabeu, Segun Fatumo
Summary of Session 3
Franca Fraternali
Break
Session 4: Federated Analytics/Learning
Session Lead: Phil Quinlan, Honorary Professor and Director of Health Informatics, University of Nottingham
Talk 1: Thomas Giles, Team Leader, The Digital Research Service, The University of Nottingham
Tools to enable rapid discoverability of secure healthcare datasets (CaRROT and HUTCH
Talk 2: Emily Jefferson, Health Informatics Centre (HIC) Director, University of Dundee
Recommendations for disclosure control of trained Machine Learning (ML) models from Trusted Research Environments (TREs)
Talk 3: Hugh Garner, Full Stack Developer, Newcastle University
Privacy-preserving federated analysis with DataSHIELD: methods and experiences
Breakout Discussions:
Thomas Giles, Emily Jefferson and Hugh Garner with Phil Quinlan
Lunch
Summary of Session 4
Phil Quinlan
Session 5: Structural Bioinformatics
Session Lead: Mark Wass, School of Biosciences, University of Kent
Talk 1: Joe Marsh, Group Leader, MRC Human Genetics Unit, University of Edinburgh
Interpreting variant effects through the lens of protein structure
Talk 2: Yana Bromberg, Professor, Rutgers University School of Environmental and Biological Sciences
Protein fossils: metal binding then and now
Talk 3: Michael Tress, Bioinformatics Unit, Spanish National Cancer Research Centre (CNIO)
AlphaFold, Model Structures and Genome annotation
Break
Breakout Discussions: Structural Bioinformatics
Joe Marsh, Yana Bromberg and Michael Tress
Summary of Structural Bioinformatics Session
Mark Wass, School of Biosciences, University of Kent
Session 6: Open Science
Session Lead: Yo Yehudi, Executive Director, Open Life Science
Talk 1: Batool Almarzouq, Postdoctoral Researcher, King Abdullah International Medical Research Centre / University of Liverpool
Leveraging Open Science in machine learning and bioinformatics
Talk 2: Piraveen (Piv) Gopalasingam, European Bioinformatics Institute (EMBL-EBI)
Open science training and equitable exchanges in global collaborations
Talk 3: John Ogunsola, School of Biodiversity, One Health & Veterinary Medicine, University of Glasgow
Global Distribution of APOL1 Genetic variants: a case study into equitable measurement of global genomics
Break
Breakout Discussions:
Batool Almarzouq, Piraveen Gopalasingam and John Ogunsola
Summary of Session 6
Yo Yehudi
Lunch
Session 7: Spatial Transcriptomics
Session Lead: Sarah Teichmann, Head of Cellular Genetics and Senior Group Leader, Wellcome Sanger Institute
Talk 1: Catalina Vallejos, Group Leader, MRC Human Genetics Unit at University of Edinburgh and The Alan Turing Institute
Scalable Bayesian methods to robustly quantify cell-to-cell molecular variability
Talk 2: Mo Lotfollahi, Helmholtz Munich / Welcome Sanger Institute
AI to understand health and disease using single-cell atlases
Talk 3: Emma Dann, PhD Student in Computational Biology, Cellular Genetics Programme, Wellcome Sanger Institute
Mapping the developing human immune system across organs
Breakout Discussions: Spatial Transcriptomics
Catalina Vallejos, Mo Lotfallahi and Emma Dan
Break
Summary of Spatial Transcriptomics
Sarah Teichmann, Head of Cellular Genetics and Senior Group Leader, Wellcome Sanger Institute
Keynote Lecture
Serena Scollen, Head of Human Genomics and Translational Data at ELIXIR
Talk: Towards cross-border access to human genomes at scale for research and healthcare
Funders' Perspective
Ian Lewis - Head of Transformative Technologies, UKRI - Biotechnology and Biological Sciences Research Council (BBSRC)
Transformative Technologies in the Biosciences
Event close
Carole Goble, University of Manchester and Joint Head of Node of Elixir-UK
Terms and conditions
Please carefully review our standard online event booking terms and conditions prior to registering for this event. Completing an online registration and associated payment process will mean that you are bound by these terms and conditions. Any supplemental terms or changes to these conditions on a per event basis will be included on this page. If you have any queries regarding our events or in relation to your booking, please contact us at training@earlham.ac.uk. & Assistant to Head of Research e-Infrastructure
Registration deadline: 26 September 2022
Participation: Open to all