Year in industry.

EI’s Year in Industry programme offers something a little unique to undergraduates - an experience of life at EI through the eyes of a project. Our students spend the first few weeks at EI getting to know everyone and everything from project design and scheduling, to generating libraries and loading sequencing platforms, to downstream bioinformatic analysis, including assembly and annotation. Through spending time with a number of research groups, students gain an understanding of the wide range of projects taking place at EI. It is at this point that students are presented with a range of available research projects to choose from. This forms focus of their placement from mid-November to completion.

Applications are now closed.

For more information contact Dr Emily Angiolini at yii@earlham.ac.uk.

Emily Angiolini

Emily Angiolini
Scientific Training and Education Team Manager

Projects.

Automated design and testing of rRNA probes to remove ribosomal RNA from non-model organisms.

Leah Clissold & Dr Jay Moore

Ribosomal RNAs (rRNA) and transfer RNA (tRNA) make up 80-90% of a total RNA sample and dominate sequencing reads, making it difficult to study lowly expressed genes. The aim of this project is to design and validate (both in the lab and bioinformatically) sets of hybridization probes for removing rRNA from a range of organisms. Once probes have been designed and synthesised, the student will validate them in the lab, both by hand (low-throughput) and subsequently, by transferring them to our automation platforms (high-throughput).

Projects.

Identification of host targets of wheat yellow rust effectors.

Dr Diane Saunders

Wheat yellow rust disease, caused by the fungus Puccinia striiformis f. sp tritici (PST), can lead to significant reductions in both grain quality and yield in susceptible wheat cultivars. Plant pathogens deliver effector proteins to their hosts to enable parasitic colonisation, but to date, not a single effector has been verified for PST. This project aims to utilise bioinformatics resources to refine the list of candidate effectors for PST by beginning to uncover the underlying mechanisms that may be targeted and manipulated by the pathogen to promote disease progression.

Projects.

Investigating improvements to the PAREsnip algorithm using 4-way partitioned trees.

Dr Leighton Folkes

Small RNAs (sRNAs) are a class of short (20-25 nt) non-coding RNAs that play important regulatory roles in gene expression and confidently identifying sRNA targets is an essential first step in understanding their function. A software tool called PAREsnip allows users to search for potential targets of all sRNAs obtained from high-throughput sequencing experiments. The aim of this project is to investigate potential improvements to the core algorithms within the PAREsnip software that identifies sRNA targets, with the student gaining an in-depth knowledge of sRNA target analysis using programming and high performance computing.

Eligibility.

Open to UK undergraduate students only You must be a enrolled in a degree with a year in industry degree programme or degree program that offers an optional year out, currently not studying in either your first or final year, and studying one of the following disciplines:

  • Biological sciences
  • Natural sciences
  • Biochemistry
  • Computer science
  • Mathematics
  • Physics

How it works.

  • Advertised in October and closes in November
  • Interview date early December
  • Contracts finalised in February
  • Rotation between September and November, including feedback
  • Project selection in November
  • Presentation to EI staff at end of placement
  • Report on progress
  • 12 months post placement feedback

Apply.

The Year in Industry Programme offers a unique opportunity to engage with research and training at EI for one academic year.

  • You will engage with various groups at EI through a rotation period, settling on a project for the remainder of the placement in November.
  • Secondments are from mid-September to the end of August.

For more information, you can contact Emily Angiolini, our Scientific Training & Skills Team Manager, at yii@earlham.ac.uk.

Applications are now closed.

Year in industry - apply